Short-term perinatal oxygen exposure may impair lung development in adult mice
نویسندگان
چکیده
منابع مشابه
Neonatal exposure to 65% oxygen durably impairs lung architecture and breathing pattern in adult mice.
STUDY OBJECTIVE To test the hypothesis that exposure to hyperoxia during the postnatal period of rapid alveolar multiplication by septation would cause permanent impairments, even with moderate levels of hyperoxia. DESIGN We exposed mouse pups to 65% O(2) (hyperoxic mice) or normoxia (normoxic mice) during their first postnatal month, and we analyzed lung histology, pulmonary mechanics, blood...
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ژورنال
عنوان ژورنال: Biological Research
سال: 2020
ISSN: 0717-6287
DOI: 10.1186/s40659-020-00318-y